Rare Oncology News
Advertisement
Disease Profile
Mal de debarquement syndrome
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.
Unknown
Age of onset
All ages
ICD-10
H81.8
Inheritance
Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.
Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.
X-linked
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
X-linked
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.
Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.
Not applicable
Other names (AKA)
MdDS; Mal de debarquement; Sickness of disembarkment;
Categories
Ear, Nose, and Throat Diseases; Nervous System Diseases
Summary
Mal de debarquement
Treatment
Organizations
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Organizations Supporting this Disease
-
MdDS Foundation
22406 Shannondell Drive
Audubon, PA 19403
E-mail: [email protected]
Website: https://www.mddsfoundation.org -
Vestibular Disorders Association
5018 NE 15th Ave
Portland, OR 97211
Toll-free: 800-837-8428
Telephone: 503-229-7705
Fax: 503-229-8064
E-mail: [email protected]
Website: https://www.vestibular.org
Social Networking Websites
- Visit the following Facebook groups related to Mal de debarquement syndrome:
(Mal de Debarquement Syndrome) MdDS Friends
Learn more
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Where to Start
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The National Institute on Deafness and Other Communication Disorders (NIDCD) conducts and supports biomedical and behavioral research and research training in the normal and disordered processes of hearing, balance, smell, taste, voice, speech, and language. Click on the link to view information on this topic.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
In-Depth Information
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Mal de debarquement syndrome. Click on the link to view a sample search on this topic.
Selected Full-Text Journal Articles
- Cha YH, Cui Y, Baloh RW. Repetitive transcranial magnetic stimulation for Mal de Debarquement Syndrome Otol Neurotol. 2013 Jan; 34(1):175-179.
- Dai M, Cohen B, Smouha E, Cho C. Readaptation of the Vestibulo-Ocular Reflex Relieves the Mal de Debarquement Syndrome Front Neurol. 2014 Jul 15; 5:124.
- Yuan H, Shou G, Gleghorn D, Ding L, Cha YH. Resting State Functional Connectivity Signature of Treatment Effects of Repetitive Transcranial Magnetic Stimulation in Mal de Debarquement Syndrome. Brain Connect. 2017 Nov 1; 7(9):617-626.
- Dai M, Cohen B, Cho C, Shin S, Yakushin SB. Treatment of the Mal de Debarquement Syndrome: A 1-Year Follow-up. Front Neurol. 2017 May 5; 8:175.
- Cha YH, Deblieck C, Wu AD. Double-blind sham-controlled cross-over trial of repetitive transcranial magnetic stimulation for Mal de Debarquement Syndrome. Otol Neurotol. 2016 Jul; 37(6):805-812.
- Cha YH, Urbano D, Pariseau N. Randomized Single Blind Sham Controlled Trial of Adjunctive Home-Based tDCS after rTMS for Mal De Debarquement Syndrome: Safety, Efficacy, and Participant Satisfaction Assessment. Brain Stimulation. 2016 July-Aug; 9(4):537-544.
- Van Ombergen A, Van Rompaey V, Maes LK, Van de Heyning PH, Wuyts FL. Mal de debarquement syndrome: a systematic review. J Neurol. 2016; 263:843-854.
- Nwagwu V, Patel R, Okudo J. Mal de Debarquement Syndrome: A Rare Entity—A Case Report and Review of the Literature. Case Rep Otolaryngol. 2015 Aug 5; 2015.
- Cha YH, Chakrapani S. Voxel Based Morphometry Alterations in Mal de Debarquement Syndrome. PLoS One. 2015 Aug 7; 10(8):e0135021.
References
- About Mal de Débarquement Syndrome. MdDS Foundation. https://mddsfoundation.org/about/. Accessed 1/11/2018.
- Kramer J. Mal de Debarquement. National Organization for Rare Disorders (NORD). 2017; https://rarediseases.org/rare-diseases/mal-de-debarquement/.
- Cha YH. Mal de debarquement syndrome: new insights. Ann N Y Acad Sci. 2015 Apr; 1343:63-8. https://www.ncbi.nlm.nih.gov/pubmed/25726862.
- Dai M, Cohen B, Smouha E, Cho C. Readaptation of the Vestibulo-Ocular Reflex Relieves the Mal De Debarquement Syndrome. Front Neurol. 2014 Jul 15; 5:124. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097942/.
- Cha YH, Cui Y, Baloh RW. Repetitive transcranial magnetic stimulation for Mal de Debarquement Syndrome. Otol Neurotol. 2013 Jan; 34(1):175-179. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529198/.
- Shou G, Yuan H, Urbano D, Cha YH, Ding L. Changes of symptom and EEG in mal de debarquement syndrome patients after repetitive transcranial magnetic stimulation over bilateral prefrontal cortex: a pilot study. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:4294-7. https://www.ncbi.nlm.nih.gov/pubmed/25570942.
Rare Oncology News